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Thursday, July 5, 2012
NATO troop supplies set to resume via Pakistan
Pakistani men paint an oil tanker, which was used to transport NATO fuel supplies to Afghanistan, while parked with other tankers in Karachi, Pakistan, Tuesday, July 3, 2012. The Obama administration said Tuesday that Pakistan was reopening its supply lines into Afghanistan, after the U.S. belatedly issued an apology for the November killing of 24 Pakistani troops in a NATO airstrike. (AP Photo/Shakil Adil)
Pakistani men paint an oil tanker, which was used to transport NATO fuel supplies to Afghanistan, while parked with other tankers in Karachi, Pakistan, Tuesday, July 3, 2012. The Obama administration said Tuesday that Pakistan was reopening its supply lines into Afghanistan, after the U.S. belatedly issued an apology for the November killing of 24 Pakistani troops in a NATO airstrike. (AP Photo/Shakil Adil)
Drivers of oil tankers, which were used to transport NATO fuel supplies to Afghanistan, dance celebrating the news that Pakistan will reopen NATO supply routes, in Karachi, Pakistan, Tuesday, July 3, 2012. The Obama administration said Tuesday that Pakistan was reopening its supply lines into Afghanistan, after the U.S. belatedly issued an apology for the November killing of 24 Pakistani troops in a NATO airstrike. (AP Photo/Shakil Adil)
A Pakistani man prays between oil tankers, which were used to transport NATO fuel supplies to Afghanistan, and parked in Karachi, Pakistan, Tuesday, July 3, 2012. The Obama administration said Tuesday that Pakistan was reopening its supply lines into Afghanistan, after the U.S. belatedly issued an apology for the November killing of 24 Pakistani troops in a NATO airstrike. (AP Photo/Shakil Adil)
A Pakistani man sleeps on top of an oil tanker, which was used to transport NATO fuel supplies to Afghanistan, while parked with other tankers in Karachi, Pakistan, Tuesday, July 3, 2012. The Obama administration said Tuesday that Pakistan was reopening its supply lines into Afghanistan, after the U.S. belatedly issued an apology for the November killing of 24 Pakistani troops in a NATO airstrike. (AP Photo/Fareed Khan)
A Pakistani mechanic works on an oil tanker, which was used to transport NATO fuel supplies to Afghanistan, while parked with other tankers in Karachi, Pakistan, Tuesday, July 3, 2012. The Obama administration said Tuesday that Pakistan was reopening its supply lines into Afghanistan, after the U.S. belatedly issued an apology for the November killing of 24 Pakistani troops in a NATO airstrike. (AP Photo/Shakil Adil)
ISLAMABAD (AP) ? Trucks carrying NATO troop supplies are set to resume shipments to Afghanistan on Wednesday following a deal between the U.S. and Pakistan that ended Islamabad's seven-month blockade.
A customs official at one of Pakistan's two main border crossings ? Chaman in southwestern Baluchistan province ? said he received orders from the government to begin allowing trucks to cross into Afghanistan at 2 p.m. local time. He spoke on condition of anonymity because he was not authorized to talk to the media.
Officials at the Torkham crossing in the Khyber tribal area were still waiting to receive word from the government, said customs officer Asfandyar Khan.
Pakistan agreed to reopen the supply line Tuesday after the U.S. said it was sorry for American airstrikes that killed 24 Pakistani soldiers in November. The attack prompted Pakistan to close the route and severely damaged already strained relations between the two countries.
Pakistan's Cabinet on Wednesday endorsed the decision to reopen the route, which was made by senior civilian and military officials.
The accord will help patch up the U.S.-Pakistan relationship, which is crucial for American efforts to stabilize Afghanistan, but the two continue to have serious differences that threaten prospects in the war-torn country.
The U.S. could save hundreds of millions of dollars since Pakistan's blockade had forced Washington to rely more heavily on a longer, costlier route that runs into Afghanistan through Central Asia. Pakistan is also expected to gain financially since the U.S. intends to free up $1.1 billion in military aid that had been frozen for the past year.
But the deal carries risks for both governments.
Pakistan is likely to face a domestic backlash given rampant anti-American sentiment in the country and the government's failure to force the U.S. to stop drone attacks and accede to other demands made by parliament.
The Pakistani Taliban vowed to attack trucks carrying NATO supplies once they started moving, calling the government a slave to the U.S.
President Barack Obama risks exposing himself to criticism from Republicans, including presidential challenger Mitt Romney, who contends the administration is too quick to apologize in foreign policy matters. Anger at Pakistan is high in Washington because of the country's alleged support for militants fighting U.S. troops in Afghanistan.
This risk led the U.S. to hold off apologizing to Pakistan for months, despite repeated demands from Islamabad. In the end, Secretary of State Hillary Rodham Clinton said the U.S. was "sorry" for the deaths of the Pakistani troops, but didn't offer the "unconditional apology" demanded by the country's parliament.
Clinton reiterated that mistakes on both sides led to the airstrikes on two army posts on the Afghan border, disputing Pakistan's claim that the U.S. was wholly at fault and carried out the attack deliberately.
Pakistan also demanded much higher transit fees during the months of negotiations ? up to $5,000 per truck ? but agreed in the end to maintain the $250 price levied before the attack. The U.S. offered extensive road construction projects to sweeten the deal, although officials have not provided specific figures.
Critics of the U.S. in Pakistan will likely seize on the lukewarm apology, static fees and continued American drone strikes to accuse Islamabad of selling out to Washington.
The most vocal opposition to reopening the NATO supply line has come from a collection of hardline Islamist religious leaders and politicians known as the Difah-e-Pakistan, or Defense of Pakistan Council.
The group, which many suspect was supported by the Pakistani army to pressure the U.S., plans to launch a protest campaign against the supply route decision, said chairman Maulana Samiul Haq.
"It is an insult to our nation," he said. "The rulers have put national interest at stake just to please America."
____
Associated Press writers Riaz Khan in Peshawar, Pakistan, and Matiullah Achackzai in Chaman, Pakistan, and Asif Shahzad in Islamabad contributed to this report.
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matthewverygood: RT @KenTremendous: Not to sound overly patriotic, but when I watch baseball on the Fourth of July I sincerely feel like all other countr ...
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Wednesday, July 4, 2012
RPG Grinsia (for Android)
Like?Symphony of Eternity($2.99, 4 stars) and RPG Aeon Avenger ($3.99, 3.5 stars), RPG Grinsia ($7.99 on Google Play) is a traditional, top-down Japanese RPG for most Android phones and tablets with a fantasy setting, cute little cartoon characters, and turn-based combat. Unlike in some of its competition, Grinsia starts you out with a pre-formed party: a family of "treasure hunters" who quickly get drawn into a plan to protect some ancient artifacts from a predatory empire. Translation and character development are actually pretty good here, and you can answer simple yes/no questions in the dialog interface. There's even a bit of comedy.
Grinsia takes place in three scales: a zoomed-in town mode, a zoomed-out walkable world map, and a turn-based battle interface. Battles are more tedious than in the other Kemco games I've played, because fighting always seems to require one too many taps, there's a tedious little XP-acquisition sequence at the end of every battle, and there's very little user choice in terms of acquiring skills and abilities. In a game where you're constantly running into invisible random monster encounters, that's an issue.
Grinsia's other challenge is that it seems to be easy to get stuck; I had trouble about five hours in with a cave where the game's UI elements seemed to be blocking the way out, for instance, and I've seen other complaints online about different locations. There have been a few minor version updates since I played through, though, so those sticky points may have been cleared up by now.
Grinsia isn't a must-buy like Kemco's classic Symphony of Eternity. There just isn't as much fun character-building involved, and the battles don't go as smoothly. But, for eight dollars with no additional purchases necessary, it's a decent plot-driven RPG.
For more Android App Reviews, see:
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??? Symphony of Eternity (for Android)
??? RPG Grinsia (for Android)
??? RPG Aeon Avenger (for Android)
??? Chrome (for Android)
?? more
Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/Q5hbl4jwHao/0,2817,2406393,00.asp
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KISS bring 'Monster' to UK
U.S rock band KISS members, from left, Tommy Thayer, Paul Stanley, Gene Simmons and Eric Singer, with their new book 'Monster' which contains photographs of the band's 40 year career live on stage, following a press conference in London, ahead of a concert on July 4 in aid of Help For Heroes. (AP Photo/Joel Ryan)
U.S rock band KISS members, from left, Tommy Thayer, Paul Stanley, Gene Simmons and Eric Singer, with their new book 'Monster' which contains photographs of the band's 40 year career live on stage, following a press conference in London, ahead of a concert on July 4 in aid of Help For Heroes. (AP Photo/Joel Ryan)
U.S rock band KISS members, from left, Tommy Thayer, Paul Stanley, Gene Simmons and Eric Singer, with their new book 'Monster' which contains photographs of the band's 40 year career live on stage, following a press conference in London, ahead of a concert on July 4 in aid of Help For Heroes. (AP Photo/Joel Ryan)
LONDON (AP) ? American glam rockers KISS are unleashing their "Monster" on the UK public.
The band ? Gene Simmons, Paul Stanley, Tommy Thayer and Eric Singer? was in London on Tuesday to launch its new retrospective book, "KISS Monster," and to hold a news conference.
The limited edition book ? which is three feet (1 meter) tall ? features unseen photographs from the band's 40-year career.
"A band that is bigger than life deserves a book that's bigger than life. You could call it a coffee table book, but if you put legs on it, it is a coffee table," joked Stanley.
Only 1,000 copies of "KISS Monster" will be on sale and each one will be signed by the band. It will retail at a staggering >2,742 ($4,299).
"It's not a cheap book because it is hand bound, hand put together. It's the Rolls-Royce of books," said Simmons.
"KISS Monster" is now on sale in the U.K.
___
Online: www.kissmonsterbook.com
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Tuesday, July 3, 2012
Lymph node roundabout
Monday, July 2, 2012
\An organism's ability to make new antibodies and use them to optimize its own immune defenses is of central importance in the fight against pathogens. In the case of severe infections, the overall relative speed with which an immune response proceeds could mean the difference between life and death. An international team of scientists, among them systems immunologist Prof. Michael Meyer-Hermann of the Helmholtz Centre for Infection Research (HZI) of Braunschweig, Germany, has now found that asymmetric division of antibody-producing B cells speeds up the body's immune defenses. Early on, one daughter cell starts making antibodies while the other works at refining its own antibodies. The researchers' findings are due to be published in the upcoming issue of the scientific journal, Cell Reports.
Our immune system produces antibodies as effective long-term weapons against viral or bacterial infections or following vaccination. Antibodies are made in lymph nodes by specialized cells called B lymphocytes. In certain areas within a lymph node - called germinal centers - these B cells first undergo a process of selection.
B cells proliferate, mutate, and thereby change their antibodies. The immune system then checks to make sure whether or not these mutations translate into an improved immune response. If so, the cells in question are selected. The final outcome is the production of optimized antibodies capable of efficiently attaching to a particular pathogen and thereby inactivating it or labeling it for subsequent destruction by phagocytic scavenger cells. "As part of this evolutionary process, the immune system takes turns between chance mutations and best-candidate-selection," explains Michael Meyer-Hermann, Director of the HZI's Department of Systems Immunology and professor of systems biology at the Technische Universit?t Braunschweig. "We are calling it the 'recycling hypothesis'." All of this allows the immune system to make sure that any antibody it produces is maximally effective against the particular pathogen it is looking to fight.
A year and a half ago, an international team of New York-based and HZI researchers described this process of antibody optimization experimentally in great detail. However, up until now, the nature of the trade-off relationship between mutation and selection was unclear. "There has been a lot of debate about whether or not one should picture this process as a one-way street or as a roundabout," says Meyer-Hermann. As the study's first author, Meyer-Hermann has analyzed his colleagues' experimental results mathematically and determined that the earlier measurements are only compatible with the idea of a roundabout.
At the beginning of the year, a team of British researchers from London showed that B cell division is asymmetric, resulting in production of unequal daughter cells. At first, the purpose of this kind of asymmetric cellular division seemed uncertain. Meyer-Hermann's analyses suggest that one of the two daughter cells leaves the germinal center and starts producing antibodies while the other stays behind and undergoes another round of mutation and selection inside the germinal center. The mathematical model illustrates the advantage of this type of set-up. While one fairly specialized daughter cell is already making antibodies, its clone, which can be further optimized in the next round, stays behind. Compared with symmetric division, in asymmetric division there is a tenfold increase in the number of antibodies produced. In addition, the cell that stays behind in the germinal center stores information regarding a successful antibody it has produced, and the optimization process thus concludes more quickly. "This kind of time-saving in antibody production can be a real life-saver in the case of a dangerous infection," explains Michael Meyer-Hermann.
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Helmholtz Centre for Infection Research: http://www.helmholtz-hzi.de/en
Thanks to Helmholtz Centre for Infection Research for this article.
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Source: http://www.labspaces.net/121372/Lymph_node_roundabout
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